Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-(2,4-Bis-trifluoromethyl-benzyloxy)-3-methoxy-phenyl]-2-cyano-N-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-acrylamide
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 PubChem ID
CID: 6918788
SID: 12015852
Canonical SMILES
COc1cc(\C=C(/C#N)C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F
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Compound Formula C23H13F9N4O3S
Compound Structure
Protein Name
 Protein Info 
Steroid hormone receptor ERR1
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group B
>
Nuclear hormone receptor subfamily 3 group B member 1
Uniprot ID
P11474
Gene Name
ESRRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 270 nM
   TI
   LI
   LO
   TS
2
IC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61.33 nM
2 IC50 = 370 nM