Brief Information of the Compound and Protein
Compound Name
N-(5-fluoro-2-piperazin-1-ylphenyl)-2-(5-methoxy-3-oxo-1H-isoindol-2-yl)-1,3-thiazole-4-carboxamide
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PubChem ID
CID: 24954092
SID: 56251942
Canonical SMILES
COc1ccc2CN(C(=O)c2c1)c1nc(cs1)C(=O)Nc1cc(F)ccc1N1CCNCC1
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Compound Formula C23H22FN5O3S
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CAMK protein kinase group
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CAMK protein kinase CAMK1 family
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CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 6000 nM
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