Brief Information of the Compound and Protein
Compound Name
2-(1H-indazol-3-ylamino)-N-(2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide
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PubChem ID
CID: 24968463
SID: 56266616
Canonical SMILES
O=C(Nc1ccccc1N1CCNCC1)c1csc(Nc2n[nH]c3ccccc23)n1
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Compound Formula C21H21N7OS
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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CAMK protein kinase group
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CAMK protein kinase CAMK1 family
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CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 350 nM
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