Brief Information of the Compound and Protein
Compound Name
2-(1H-indol-5-yl)-N-(4-piperazin-1-ylpyridin-3-yl)-1,3-thiazole-4-carboxamide
    Show/Hide
PubChem ID
CID: 71602948
SID: 163684198
Canonical SMILES
O=C(Nc1cnccc1N1CCNCC1)c1csc(n1)-c1ccc2[nH]ccc2c1
    Show/Hide
Compound Formula C21H20N6OS
Compound Structure
Protein Name
Serine/threonine-protein kinase Chk1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase CAMK1 family
>
CAMK protein kinase CHK1 subfamily
Uniprot ID
O14757
Gene Name
CHEK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS