Brief Information of the Compound and Protein
Compound Name
2,2,2-trifluoroethyl 4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]piperazine-1-carboxylate
    Show/Hide
PubChem ID
CID: 51030985
SID: 117691053
Canonical SMILES
FC(F)(F)COC(=O)N1CCN(CC1)c1ncc(OCc2ccncc2C#N)cn1
    Show/Hide
Compound Formula C18H17F3N6O3
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q7TQP3
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000107 HEK293S Homo sapiens (Human)  1
1
EC50 = 698 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4985 nM
   TI
   LI
   LO
   TS