Brief Information of the Compound and Protein
Compound Name
N-tert-butyl-2-(6-methoxyindazol-1-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
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PubChem ID
CID: 71279723
SID: 163619342
Canonical SMILES
COc1ccc2cnn(-c3cnc4[nH]cc(C(=O)NC(C)(C)C)c4n3)c2c1
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Compound Formula C19H20N6O2
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 129 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 33 nM