Brief Information of the Compound and Protein
Compound Name
N-propan-2-yl-2-(1,5,5-trimethyl-6,7-dihydro-4H-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
    Show/Hide
PubChem ID
CID: 71280420
SID: 163618996
Canonical SMILES
CC(C)NC(=O)c1c[nH]c2ncc(nc12)-c1nn(C)c2CCC(C)(C)Cc12
    Show/Hide
Compound Formula C20H26N6O
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 738 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 132 nM