Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-tert-butyl-2-[5-(difluoromethoxy)-1-(3,4-dihydroxybutyl)indazol-3-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
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 PubChem ID
CID: 71279672
SID: 163618893
Canonical SMILES
CC(C)(C)NC(=O)c1c[nH]c2ncc(nc12)-c1nn(CCC(O)CO)c2ccc(OC(F)F)cc12
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Compound Formula C23H26F2N6O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM
2 IC50 = 534 nM