Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[6-fluoro-1-(3-methylsulfonylpropyl)indazol-3-yl]-N-(1-hydroxy-2-methylpropan-2-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
    Show/Hide
 PubChem ID
CID: 71279507
SID: 163618994
Canonical SMILES
CC(C)(CO)NC(=O)c1c[nH]c2ncc(nc12)-c1nn(CCCS(C)(=O)=O)c2cc(F)ccc12
    Show/Hide
Compound Formula C22H25FN6O4S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM
2 IC50 = 94 nM