Brief Information of the Compound and Protein
Compound Name
2-(6-chloroindazol-1-yl)-N-(1-hydroxy-2-methylpropan-2-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
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PubChem ID
CID: 71288435
SID: 163619446
Canonical SMILES
CC(C)(CO)NC(=O)c1c[nH]c2ncc(nc12)-n1ncc2ccc(Cl)cc12
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Compound Formula C18H17ClN6O2
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 132 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM
2 IC50 = 9950 nM