Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BIIB-057
    Show/Hide
 PubChem ID
CID: 44462758
SID: 85742094
Canonical SMILES
N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1
    Show/Hide
Compound Formula C19H23N9O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 178 nM
   TI
   LI
   LO
   TS
2
IC50 = 223 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM
2 IC50 = 6 nM
3 IC50 = 13 nM
4 IC50 = 540 nM