Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3'-[(1-acetylpiperidin-4-yl)methyl]-2'-amino-6-(3-chlorophenyl)-2,2-dimethylspiro[3H-chromene-4,5'-imidazole]-4'-one
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 PubChem ID
CID: 68321923
Canonical SMILES
CC(=O)N1CCC(CN2C(N)=NC3(CC(C)(C)Oc4ccc(cc34)-c3cccc(Cl)c3)C2=O)CC1
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Compound Formula C27H31ClN4O3
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 75 nM
   TI
   LI
   LO
   TS