Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2'-amino-6-(5-chloropyridin-3-yl)-2,2,3'-trimethylspiro[1,3-dihydronaphthalene-4,6'-5H-pyrimidine]-4'-one
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 PubChem ID
CID: 66683677
Canonical SMILES
CN1C(N)=NC2(CC1=O)CC(C)(C)Cc1ccc(cc21)-c1cncc(Cl)c1
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Compound Formula C21H23ClN4O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 32863 nM
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