Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2'-amino-6-(3-chlorophenyl)-2,2-dimethyl-3'-(2,2,2-trifluoroethyl)spiro[3H-chromene-4,5'-imidazole]-4'-one
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 PubChem ID
CID: 68322203
Canonical SMILES
CC1(C)CC2(N=C(N)N(CC(F)(F)F)C2=O)c2cc(ccc2O1)-c1cccc(Cl)c1
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Compound Formula C21H19ClF3N3O2
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 604 nM
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