Brief Information of the Compound and Protein
Compound Name
1-(1-azabicyclo[2.2.2]octan-3-ylmethyl)-4-(1H-indol-4-yl)quinolin-2-one
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PubChem ID
CID: 71566981
SID: 163593409
Canonical SMILES
O=c1cc(-c2cccc3[nH]ccc23)c2ccccc2n1CC1CN2CCC1CC2
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Compound Formula C25H25N3O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 23 nM
   TI
   LI
   LO
   TS
2
EC50 = 540 nM
   TI
   LI
   LO
   TS