Brief Information of the Compound and Protein
Compound Name
N-[[3-[1-(1-azabicyclo[2.2.2]octan-3-ylmethyl)-2-oxoquinolin-4-yl]phenyl]methyl]methanesulfonamide
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PubChem ID
CID: 71566982
SID: 163593410
Canonical SMILES
CS(=O)(=O)NCc1cccc(c1)-c1cc(=O)n(CC2CN3CCC2CC3)c2ccccc12
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Compound Formula C25H29N3O3S
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 14 nM
   TI
   LI
   LO
   TS
2
EC50 = 260 nM
   TI
   LI
   LO
   TS