Brief Information of the Compound and Protein
Compound Name
6-(2-pyridin-2-ylethyl)-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
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PubChem ID
CID: 71525248
SID: 163518375
Canonical SMILES
Nc1nc(Nc2cccc(c2)C(F)(F)F)c2cc(CCc3ccccn3)[nH]c2n1
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Compound Formula C20H17F3N6
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  1
1
IC50 = 16700 nM
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