Brief Information of the Compound and Protein
Compound Name
4-(propan-2-ylamino)-7-(1,2-thiazol-4-yl)cinnoline-3-carboxamide
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PubChem ID
CID: 71720656
Canonical SMILES
CC(C)Nc1c(nnc2cc(ccc12)-c1cnsc1)C(N)=O
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Compound Formula C15H15N5OS
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM
2 IC50 = 20 nM