Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(13aS)-3,9,11-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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 PubChem ID
CID: 70690500
SID: 163441279
Canonical SMILES
COc1cc2C[C@@H]3N(CCc4cc(OC)c(O)cc34)Cc2c(OC)c1
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Compound Formula C20H23NO4
Compound Structure
Protein Name
 Protein Info 
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 2.53 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 4.86 nM
   TI
   LI
   LO
   TS
2
IC50 = 9.85 nM
   TI
   LI
   LO
   TS
3
Ki = 2.5 nM
   TI
   LI
   LO
   TS
4
Ki = 2.53 nM
   TI
   LI
   LO
   TS
5
Ki = 5.18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1400 nM