Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic acid [(S)-1-((S)-1-formyl-3-methyl-butylcarbamoyl)-3-methyl-butyl]-amide
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 PubChem ID
CID: 462382
SID: 14761103
Canonical SMILES
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O
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Compound Formula C26H41N3O5
Compound Structure
Protein Name
 Protein Info 
Proteasome subunit beta type-5
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28074
Gene Name
PSMB5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM
2 IC50 = 11 nM
3 IC50 = 25 nM
4 IC50 = 37 nM
5 Ki = 1.4 nM
6 Ki = 3.7 nM
7 Ki = 70 nM