Brief Information of the Compound and Protein
Compound Name
5-(5-hydroxy-2-adamantyl)-1-pyridin-2-yl-7,8-dihydro-6H-pyrazolo[4,3-c]azepin-4-one
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Canonical SMILES
O[C@]12CC3CC(C1)[C@@H](C(C3)C2)N1CCCc2c(cnn2-c2ccccn2)C1=O
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Compound Formula C22H26N4O2
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 59.3 nM
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