Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(2,3-dichlorophenoxy)-1,3-dimethyl-N-(oxolan-3-yl)-N-(pyridin-3-ylmethyl)pyrazole-4-carboxamide
    Show/Hide
 PubChem ID
CID: 71561885
SID: 163562224
Canonical SMILES
Cc1nn(C)c(Oc2cccc(Cl)c2Cl)c1C(=O)N(Cc1cccnc1)C1CCOC1
    Show/Hide
Compound Formula C22H22Cl2N4O3
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
2
EC50 = 1080 nM
   TI
   LI
   LO
   TS