Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-cyclopropyl-5-(2,3-dichlorophenoxy)-1,3-dimethyl-N-(pyridin-3-ylmethyl)pyrazole-4-carboxamide
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 PubChem ID
CID: 71561884
SID: 163562223
Canonical SMILES
Cc1nn(C)c(Oc2cccc(Cl)c2Cl)c1C(=O)N(Cc1cccnc1)C1CC1
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Compound Formula C21H20Cl2N4O2
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 7.9 nM
   TI
   LI
   LO
   TS
2
EC50 = 1020 nM
   TI
   LI
   LO
   TS