Brief Information of the Compound and Protein
Compound Name
[1,3-dimethyl-5-[2-(trifluoromethyl)phenoxy]pyrazol-4-yl]-(2-pyridin-3-ylpiperidin-1-yl)methanone
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PubChem ID
CID: 71561614
SID: 163561935
Canonical SMILES
Cc1nn(C)c(Oc2ccccc2C(F)(F)F)c1C(=O)N1CCCCC1c1cccnc1
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Compound Formula C23H23F3N4O2
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
2
EC50 = 352 nM
   TI
   LI
   LO
   TS