Brief Information of the Compound and Protein
Compound Name
N-[5-chloro-4-(3-methoxyanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide
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PubChem ID
CID: 71583635
SID: 163635672
Canonical SMILES
COc1cccc(Nc2nc(NC(=O)C(C)(C)C)nc3[nH]c4cccc(Cl)c4c23)c1
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Compound Formula C22H22ClN5O2
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000118 U-251MG Homo sapiens (Human)  1
1
IC50 = 41000 nM
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