Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[2-methyl-3-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-5-morpholin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl]urea
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 PubChem ID
CID: 71270848
SID: 163527661
Canonical SMILES
Cc1nn2c(NC(N)=O)cc(nc2c1Cc1cccc(c1C)C(F)(F)F)N1CCOCC1
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Compound Formula C21H23F3N6O2
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000481 HCC1954
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 12589.25 nM
   TI
   LI
   LO
   TS
2
EC50 > 31622.78 nM
   TI
   LI
   LO
   TS
CL000196 MDA-MB-468
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS
2
EC50 > 31622.78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19.95 nM