Brief Information of the Compound and Protein
Compound Name
3-[(2,3-dichlorophenyl)methyl]-2-ethyl-5-pyridin-4-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
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PubChem ID
SID: 163520866
Canonical SMILES
CCc1nn2c(O)cc(nc2c1Cc1cccc(Cl)c1Cl)-c1ccncc1
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Compound Formula C20H16Cl2N4O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000481 HCC1954 Homo sapiens (Human)  1
1
EC50 > 31622.78 nM
   TI
   LI
   LO
   TS
CL000196 MDA-MB-468 Homo sapiens (Human)  1
1
EC50 = 19952.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.631 nM