Brief Information of the Compound and Protein
Compound Name
5-(2-chlorophenyl)-4-(4,5-dihydrothieno[3,2-d][1]benzoxepin-2-yl)-1,3-thiazol-2-amine
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PubChem ID
CID: 57900505
Canonical SMILES
Nc1nc(-c2cc3CCOc4ccccc4-c3s2)c(s1)-c1ccccc1Cl
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Compound Formula C21H15ClN2OS2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 0.5 nM