Brief Information of the Compound and Protein
Compound Name
2-[2-(2,4-difluorophenyl)-1,2,4-triazol-3-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepine-8-carboxamide
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PubChem ID
CID: 57900428
SID: 163513236
Canonical SMILES
NC(=O)c1ccc2-c3sc(cc3CCOc2c1)-c1ncnn1-c1ccc(F)cc1F
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Compound Formula C21H14F2N4O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 0.5 nM