Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
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 PubChem ID
CID: 44259
SID: 22395183
Canonical SMILES
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
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Compound Formula C28H26N4O3
Compound Structure
Protein Name
 Protein Info 
Telomerase reverse transcriptase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O14746
Gene Name
TERT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 4140 nM
   TI
   LI
   LO
   TS
2
IC50 = 8300 nM
   TI
   LI
   LO
   TS
CL000172 MGC-803
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8970 nM
   TI
   LI
   LO
   TS
CL000171 SW1116
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8670 nM