Brief Information of the Compound and Protein
Compound Name
2-[[5-cyano-2-(4-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]amino]-N-methylbenzamide
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PubChem ID
CID: 71608474
Canonical SMILES
CNC(=O)c1ccccc1Nc1c(cnc2[nH]c(cc12)-c1ccc(F)cc1)C#N
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Compound Formula C22H16FN5O
Compound Structure
Protein Name
Focal adhesion kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Fak family
Uniprot ID
Q05397
Gene Name
PTK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
IC50 = 365 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 37 nM
2 Kd = 40 nM