Brief Information of the Compound and Protein
Compound Name
N-[1-[4-hydroxy-4-(1,3-thiazol-5-yl)cyclohexyl]azetidin-3-yl]-2-[[2-methyl-6-(trifluoromethyl)quinazolin-4-yl]amino]acetamide
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PubChem ID
SID: 131533507
Canonical SMILES
Cc1nc(NCC(=O)NC2CN(C2)[C@H]2CC[C@](O)(CC2)c2cncs2)c2cc(ccc2n1)C(F)(F)F
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Compound Formula C24H27F3N6O2S
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 8 nM
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