Brief Information of the Compound and Protein
Compound Name
N-[2-[[1-[4-(6-cyanopyridin-3-yl)-4-hydroxycyclohexyl]azetidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide
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PubChem ID
SID: 163513728
Canonical SMILES
O[C@]1(CC[C@@H](CC1)N1CC(C1)NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)c1ccc(nc1)C#N
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Compound Formula C25H26F3N5O3
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS