Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
    Show/Hide
 PubChem ID
CID: 135409468
SID: 14776686
Canonical SMILES
Clc1ccc2Nc3ccccc3C(=Nc2c1)N1CCNCC1
    Show/Hide
Compound Formula C17H17ClN4
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 48 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
2
EC50 = 140 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 60.26 nM
   TI
   LI
   LO
   TS