Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(cyclopropylmethyl)-7-[4-(3,6-difluoro-2-methoxyphenyl)piperidin-1-yl]-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
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 PubChem ID
CID: 71457757
Canonical SMILES
COc1c(F)ccc(F)c1C1CCN(CC1)c1ccn2c(CC3CC3)nnc2c1C(F)(F)F
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Compound Formula C23H23F5N4O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4.1 nM
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   LI
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   TS