Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-pyridin-2-yl-N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]thiophene-2-carboxamide
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 PubChem ID
CID: 25182691
SID: 57290369
Canonical SMILES
O=C(N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1)c1ccc(s1)-c1ccccn1
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Compound Formula C23H24N4OS
Compound Structure
Protein Name
 Protein Info 
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 30 nM
   TI
   LI
   LO
   TS