Brief Information of the Compound and Protein
Compound Name
(E)-3-(3-methylthiophen-2-yl)-N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]prop-2-enamide
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PubChem ID
CID: 71450158
SID: 163506691
Canonical SMILES
Cc1ccsc1\C=C\C(=O)N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1
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Compound Formula C21H25N3OS
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4.5 nM
   TI
   LI
   LO
   TS