Brief Information of the Compound and Protein
Compound Name
4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
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PubChem ID
CID: 4521392
SID: 87231679
Canonical SMILES
NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc2OCOc2c1)-c1ccccn1
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Compound Formula C22H16N4O3
Compound Structure
Protein Name
TGF-beta receptor type-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 2 subfamily
Uniprot ID
P37173
Gene Name
TGFBR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 66 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd > 10000 nM