Brief Information of the Compound and Protein
Compound Name
2-N-[4-methoxy-6-(oxan-4-yl)pyridin-3-yl]-4-N-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine
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PubChem ID
CID: 71460831
SID: 163502722
Canonical SMILES
CNc1nc(Nc2cnc(cc2OC)C2CCOCC2)ncc1C(F)(F)F
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Compound Formula C17H20F3N5O2
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 9 nM