Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-(2-hydroxy-2-methylpropyl)-6-methoxy-3H-isoindol-1-one
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 PubChem ID
CID: 71451850
SID: 163502724
Canonical SMILES
CCNc1nc(Nc2cc3CN(CC(C)(C)O)C(=O)c3cc2OC)ncc1C(F)(F)F
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Compound Formula C20H24F3N5O3
Compound Structure
Protein Name
 Protein Info 
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3 nM
2 Ki = 4 nM