Brief Information of the Compound and Protein
Compound Name
2-[3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl]-3,4-dihydro-1H-isoquinoline
    Show/Hide
PubChem ID
CID: 57459517
SID: 163457331
Canonical SMILES
FC(F)(F)c1c(ccn2c(CC3CC3)nnc12)N1CCc2ccccc2C1
    Show/Hide
Compound Formula C20H19F3N4
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 149 nM
   TI
   LI
   LO
   TS