Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[2-(3-chlorophenyl)-5-methylpyrazol-3-yl]-5-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 58063487
SID: 163502835
Canonical SMILES
CNc1ccn2ncc(C(=O)Nc3cc(C)nn3-c3cccc(Cl)c3)c2n1
    Show/Hide
Compound Formula C18H16ClN7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 259 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.1 nM