Brief Information of the Compound and Protein
Compound Name
N-[3-(3-chlorophenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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PubChem ID
CID: 66850717
SID: 163503547
Canonical SMILES
Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cccc(Cl)c1
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Compound Formula C17H13ClN6O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2 Homo sapiens (Human)  1
1
IC50 = 89.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3.2 nM