Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-amino-N-[3-(2,5-dichlorophenyl)-1-methylpyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
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 PubChem ID
CID: 58063117
SID: 160640904
Canonical SMILES
Cn1cc(NC(=O)c2cnn3ccc(N)nc23)c(n1)-c1cc(Cl)ccc1Cl
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Compound Formula C17H13Cl2N7O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.9 nM
   TI
   LI
   LO
   TS
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.1 nM