Brief Information of the Compound and Protein
Compound Name
4-(benzenesulfonyl)-11-methyl-5-methylsulfanyl-2,6,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1,3,5,8-tetraene
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PubChem ID
CID: 44476801
SID: 85757716
Canonical SMILES
CSc1nn2cc3CN(C)CCc3nc2c1S(=O)(=O)c1ccccc1
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Compound Formula C17H18N4O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 492 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 372 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 801 nM
2 Ki = 372 nM