Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(benzenesulfonyl)-11-methyl-4-methylsulfanyl-2,3,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7-tetraene
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 PubChem ID
CID: 58149665
Canonical SMILES
CSc1nn2c3CCN(C)Cc3cnc2c1S(=O)(=O)c1ccccc1
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Compound Formula C17H18N4O2S2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 14.8 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 7.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 76.9 nM
2 Ki = 35.7 nM