Brief Information of the Compound and Protein
Compound Name
2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic acid
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PubChem ID
CID: 9927531
SID: 14899825
Canonical SMILES
C\C(=C/C(=O)Nc1ccccc1C(O)=O)c1ccc2ccccc2c1
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Compound Formula C21H17NO3
Compound Structure
Protein Name
Telomerase reverse transcriptase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O14746
Gene Name
TERT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  3
1
IC50 = 93 nM
   TI
   LI
   LO
   TS
2
IC50 = 3600 nM
   TI
   LI
   LO
   TS
3
IC50 = 4600 nM
   TI
   LI
   LO
   TS
CL000111 MDA-MB-231 Homo sapiens (Human)  1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CL000172 MGC-803 Homo sapiens (Human)  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM
2 IC50 = 280 nM
3 IC50 = 410 nM
4 IC50 = 5000 nM
5 IC50 = 11570 nM