Brief Information of the Compound and Protein
Compound Name
Bisanilinopyrimidine, 12b
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PubChem ID
CID: 70702162
SID: 163439067
Canonical SMILES
Fc1cnc(Nc2ccc(cc2)-c2nnn[nH]2)nc1Nc1ccccc1Cl
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Compound Formula C17H12ClFN8
Compound Structure
Protein Name
Aurora kinase A
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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Other protein kinase group
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Other protein kinase AUR family
Uniprot ID
O14965
Gene Name
AURKA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468 Homo sapiens (Human)  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.9 nM