Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide
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 PubChem ID
CID: 5311081
SID: 14764280
Canonical SMILES
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
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Compound Formula C32H37N5O5
Compound Structure
Protein Name
 Protein Info 
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P35372
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  7
1
EC50 = 0.04 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.55 nM
   TI
   LI
   LO
   TS
3
EC50 = 5.754 nM
   TI
   LI
   LO
   TS
4
EC50 = 13.18 nM
   TI
   LI
   LO
   TS
5
EC50 = 13.8 nM
   TI
   LI
   LO
   TS
6
Ki = 2.95 nM
   TI
   LI
   LO
   TS
7
Ki = 5.3 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 11.8 nM
   TI
   LI
   LO
   TS
2
EC50 = 15.7 nM
   TI
   LI
   LO
   TS
3
EC50 = 55.5 nM
   TI
   LI
   LO
   TS
4
Ki = 3.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.69 nM
2 Ki = 1.33 nM
3 Ki = 8.23 nM