Brief Information of the Compound and Protein
Compound Name
(2S)-N-(2-oxo-5-pyridin-4-yl-1H-pyridin-3-yl)-3-phenyl-2-(1,3-thiazol-4-ylmethylamino)propanamide
    Show/Hide
PubChem ID
CID: 70682472
SID: 163436655
Canonical SMILES
O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NCc1cscn1
    Show/Hide
Compound Formula C23H21N5O2S
Compound Structure
Protein Name
Probable G-protein coupled receptor 142
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
Q7Z601
Gene Name
GPR142
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 93 nM
   TI
   LI
   LO
   TS
2
EC50 = 500 nM
   TI
   LI
   LO
   TS
3
EC50 = 930 nM
   TI
   LI
   LO
   TS